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Perricone MD Acyl-Glutathione Deep Crease Serum

Item Number:

Perricone MD Acyl-Glutathione Deep Crease Serum
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Perricone MD Acyl-Glutathione Deep Crease Serum
Video1 of Item: 462535

TSC Price: $227.00

EASY PAY®: 4 payments of $56.75

Shipping & Handling: $6.99

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What it is:
Acyl-Glutathione Deep Crease Serum contains the highest concentration of Acyl-Glutathione of any of Dr. Perricone's products plus three powerful peptides to deliver his very first comprehensive, targeted treatment product to address the biggest contributor to an aged appearance, deep creases.

Who it is for:
This product is ideal for anyone who has looked in the mirror and thought they look much older, and for the person who is experiencing one or more of the accelerated signs of facial skin aging.

What it does:
Deep Crease Serum contains the highest levels of Acyl-Glutathione found in any Perricone product. Dr. Perricone formulated this specifically to target the deep creases that are typically wider and deeper than lines and have been very difficult to treat, until now. To test the efficacy of the product, he conducted a comprehensive consumer use study across 30 days at an independent laboratory. The results even amazed Dr. Perricone; 76% of subjects reported that their deep creases appeared more shallow.

What is included:
• Acyl-Glutathione Deep Crease Serum (30ml/1fl.oz)

Ratings & Reviews


(average rating based on 7 reviews)

Ratings Distribution

  • 5 Stars



  • 4 Stars



  • 3 Stars



  • 2 Stars



  • 1 Stars




of respondents would recommend this to a friend.

Reviewed by 7 customers

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Displaying reviews 1-7

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( 1 of 1 customers found this review helpful)



By Venessa

from Toronto, Ontario

Silver Reviewer

Part of my daily beauty regime in conjunction with the correlating eyelid serum. It has rid of all early signs of ageing and increased collagen production in my skin. It is an absolute must!

( 14 of 14 customers found this review helpful)


It works for me

By Lorna

from Winnipeg

All Star Reviewer

After two months I can see a difference in reducing the wrinkles around my mouth. But unfortunately after two months the bottle is empty and its impossible to change my 90 day auto del to 60 days. The TV personality said you could change your auto del if needed. So for the next 30 days I sit and wait. This makes me very unhappy.

( 20 of 20 customers found this review helpful)


Not overly effective

By Fancy

from Strathmore Alberta

Helpful Reviewer

Was so excited to see this product "Deep Lines" and purchased the face serum & eye serum; Have been using them now for almost 2 months; I have extremely deep lines over my upper lip and around the mouth area [side of the mouth] ; Upper lip shows almost no improvement whatsoever; Mouth lines do have some visable improvement, but nothing to write home about; The eye serum does seem to "brighten" my eye area, but really, no visible improvement. I do not have dark circles under my eyes, so cannot comment on that; I think the bottom line is "deep lines are deep lines" and nothing short of a doctor's visit will ever change that. I am 60+ yrs of age and really cannot afford the price for the results I have seen.

( 8 of 11 customers found this review helpful)


Too soon to tell

By mj

from NT

It is too soon to tell how well this is working. I can say the acyl-glutathione products and the neuropeptide face cream are about the only products from this line that don't irritate my skin. I am still trying them out.

( 18 of 18 customers found this review helpful)


29 Days and No Deep Crease Reduction

By Lia

from Ottawa

Silver Reviewer

I tried many products in the past and hoped so much that this product will work and will finally see a reduction in the lines around my mouth. I waited six months for this product as the first shipment has not arrived. After using this product for 29 days, I was expecting to see a minimal reduction in the lines around the mouth, but it was not the case... I admit that the general look of the skin was good (this is the reason I gave it two stars), but that effect I can get from a less expensive product.

( 15 of 15 customers found this review helpful)


Does nothing for me!

By Karen

from Thornhill

All Star Reviewer

I guess not every product will work it's wonders on everyone. Quite disappointed since I was hoping for a miracle given how this product was promoted by its chief spokesperson!

( 19 of 19 customers found this review helpful)


42 days and no Results

By P. E.

from Bowmanville

All Star Reviewer

I am 62 yrs old. The only lines I have are around my mouth, hence my purchase. I cannot see any improvement after 42 days of using this product. I have tried other products from this line with similar results. I also purchased the eye serum with this product. I think it has improved the puffiness on my upper eyelids. I would maybe buy it again, but not this product.

Displaying reviews 1-7

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